Diabetes mellitus

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Diabetes mellitus

Diabetes type two is the most common form of ___a ____. Although it can occur at any age it is more common in people who are overweight, sedentary and over middle age.

___b____ is the main source of energy for body cells. When ____c___ levels rise, as is normal after a meal, the pancreas gland located behind the stomach secretes the ______d_________.

Insuline enters and circulates in the blood and acts in the insuline                            receptors present in _____e___, ____f____ and other tissues of the body. Binding of insuline to these receptors causes the glucose transporters to come to the cell surface. This facilitates the entry of glucose into these cells.

In diabetes type 2 the production of insuline is ____g__ and sometimes there may be resistant to insuline. The circulating insuline fails to facilitate the ______h________ into the cells and to keep the blood glucose level at optimum levels. This results in the rise of blood glucose levels.

The excess in blood glucose reacts with proteins in tissues to form what are known as Advanced Glucation End products or AGEs. AGEs create an inflammatory condition in the vasculator which causes ______i____ and damage to other organs such as the __j____ Diabetes can eventually cause damage to the heart, arteries, kidneys, nerves, eyes and skin.